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Peritoneal dialysis-related peritonitis: towards improving evidence, practices, and outcomes.

Authors
  • Cho, Yeoungjee1
  • Johnson, David W2
  • 1 Centre for Kidney Disease Research, Translational Research Institute at University of Queensland, Brisbane, Australia; Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia. , (Australia)
  • 2 Centre for Kidney Disease Research, Translational Research Institute at University of Queensland, Brisbane, Australia; Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia. Electronic address: [email protected] , (Australia)
Type
Published Article
Journal
American Journal of Kidney Diseases
Publisher
Elsevier
Publication Date
Aug 01, 2014
Volume
64
Issue
2
Pages
278–289
Identifiers
DOI: 10.1053/j.ajkd.2014.02.025
PMID: 24751170
Source
Medline
Keywords
License
Unknown

Abstract

Peritonitis is a common serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and health care costs. It also significantly limits the use of this important dialysis modality. Despite its importance as a patient safety issue, peritonitis practices and outcomes vary markedly and unacceptably among different centers, regions, and countries. This article reviews peritonitis risk factors, diagnosis, treatment, and prevention, particularly focusing on potential drivers of variable practices and outcomes, controversial or unresolved areas, and promising avenues warranting further research. Potential strategies for augmenting the existing limited evidence base and reducing the gap between evidence-based best practice and actual practice also are discussed.

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