Peripheral neuropathy and lipid-lowering therapy.
- Authors
- Type
- Published Article
- Journal
- Southern medical journal
- Publication Date
- Jul 01, 1998
- Volume
- 91
- Issue
- 7
- Pages
- 667–668
- Identifiers
- PMID: 9671841
- Source
- Medline
- License
- Unknown
Abstract
We report a case of a peripheral neuropathy induced and exacerbated by several commonly used HMG-CoA reductase inhibitors including lovastatin, simvastatin, pravastatin, and atorvastatin, and the vitamin niacin. A review of the literature shows similar cases with individual lipid-lowering drugs, but this case shows the cross-reactivity of the neuropathic process to different HMG-CoA reductase inhibitors, and it is the first reported case of a peripheral neuropathy exacerbated by the use of niacin.