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Peripheral neuropathy and lipid-lowering therapy.

Authors
  • Ziajka, P E
  • Wehmeier, T
Type
Published Article
Journal
Southern medical journal
Publication Date
Jul 01, 1998
Volume
91
Issue
7
Pages
667–668
Identifiers
PMID: 9671841
Source
Medline
License
Unknown

Abstract

We report a case of a peripheral neuropathy induced and exacerbated by several commonly used HMG-CoA reductase inhibitors including lovastatin, simvastatin, pravastatin, and atorvastatin, and the vitamin niacin. A review of the literature shows similar cases with individual lipid-lowering drugs, but this case shows the cross-reactivity of the neuropathic process to different HMG-CoA reductase inhibitors, and it is the first reported case of a peripheral neuropathy exacerbated by the use of niacin.

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