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Perineural Invasion Is an Independent Pathologic Indicator of Recurrence in Vulvar Squamous Cell Carcinoma.

Authors
  • Holthoff, Emily R
  • Jeffus, Susanne K
  • Gehlot, Ashita
  • Stone, Rebecca
  • Erickson, Stephen W
  • Kelly, Thomas
  • Quick, Charles M
  • Post, Steven R
Type
Published Article
Journal
The American Journal of Surgical Pathology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Aug 01, 2015
Volume
39
Issue
8
Pages
1070–1074
Identifiers
DOI: 10.1097/PAS.0000000000000422
PMID: 25786085
Source
Medline
License
Unknown

Abstract

PNI is an independent indicator of risk for recurrence in vSCC. The association of PNI with increased risk for recurrence, independent of DOI, nodal involvement, lymphovascular invasion, or stage, should encourage practicing pathologists to thoroughly search for and report the presence of PNI in vSCC.

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