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Peptides and Proteins Studied Using Mass Spectrometry *

Authors
  • Baldwin, Michael A.
Type
Book
Journal
Encyclopedia of Spectroscopy and Spectrometry
Publication Date
Jan 01, 1999
Pages
2089–2098
Identifiers
DOI: 10.1016/B978-0-12-374413-5.00244-X
ISBN: 978-0-12-374413-5
Source
Elsevier
Keywords
License
Unknown

Abstract

The use of mass spectrometry for the analysis of proteins and peptides is reviewed. Sample preparation and ionization methods are discussed. The use of coupled liquid chromatography is described. The approach is exemplified with a number of applications including quality control of synthetic and recombinant materials. The approaches for addressing post-translational change such as glycosylation are also given.

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