A peptide corresponding to the N-terminal 13 residues of T4 lysozyme forms an alpha-helix.
- Published Article
Wiley (John Wiley & Sons)
- Publication Date
Jan 11, 1993
Solid-phase methods have been used to synthesize LYS(1-13), a peptide corresponding to the first 13 residues of T4 lysozyme. 2D 1H NMR techniques were used to investigate its solution structure in the presence of SDS micelles. The identification of numerous medium-range NOESY crosspeaks and several slowly exchanging NH protons indicated the presence of an alpha-helical structure. This was confirmed by simulated annealing calculations performed using XPLOR.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/8422925