Affordable Access

Pentaketides relating to aspinonene and dihydroaspyrone from a marine-derived fungus, Aspergillus ostianus.

Authors
  • Kito, Keijiro
  • Ookura, Ryuhei
  • Yoshida, Sanae
  • Namikoshi, Michio
  • Ooi, Takashi
  • Kusumi, Takenori
Type
Published Article
Journal
Journal of natural products
Publication Date
Dec 01, 2007
Volume
70
Issue
12
Pages
2022–2025
Identifiers
PMID: 17994702
Source
Medline
License
Unknown

Abstract

Three new pentaketides, aspinotriols A ( 1) and B ( 3) and aspinonediol ( 5), were isolated together with two known compounds, aspinonene ( 7) and dihydroaspyrone ( 9), from the marine fungus Aspergillus ostianus strain 01F313, which was collected in Pohnpei and cultured with bromine-modified artificial seawater. The structures of the new compounds were determined by spectroscopic analyses including 1D and 2D NMR. Although 1 and 3 are diastereomers, they show nearly superimposable (1)H and (13)C NMR spectra. The absolute configurations of compounds 1, 3, 5, and 9 were elucidated by the modified Mosher's method.

Report this publication

Statistics

Seen <100 times