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Pediatric stroke as the presenting symptom of new-onset type 1 diabetes mellitus without DKA: case report and literature review

Authors
  • Bharill, Sonum A.
  • Hunter, Janel D.
  • Walsh, Elizabeth T.
  • Crudo, David F.
  • Constantacos, Cathrine
Type
Published Article
Journal
Journal of Pediatric Endocrinology and Metabolism
Publisher
Walter de Gruyter GmbH
Publication Date
Jul 19, 2019
Volume
32
Issue
9
Pages
1035–1037
Identifiers
DOI: 10.1515/jpem-2019-0222
Source
De Gruyter
Keywords
License
Yellow

Abstract

Background Stroke and other neurologic complications are rare in pediatric type 1 diabetes mellitus (T1DM) without severe diabetic ketoacidosis (DKA) or poor glycemic control. Case presentation A previously healthy, 10-year-old female presented with acute thalamic stroke, non-acidotic new T1DM diagnosis and negative hypercoagulopathy workup. She received routine insulin therapy and aspirin, and returned to neurologic baseline within a year without stroke recurrence. Conclusions The contribution of non-acidotic hyperglycemia to stroke risk is better described in adults. Even though unable to prove causality, this case should at least raise awareness of the possible association of pediatric new-onset diabetes and stroke for optimal outcomes.

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