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Pediatric MR elastography of hepatic fibrosis: principles, technique and early clinical experience.

Authors
  • Binkovitz, Larry A
  • El-Youssef, Mounif
  • Glaser, Kevin J
  • Yin, Meng
  • Binkovitz, Anna K
  • Ehman, Richard L
Type
Published Article
Journal
Pediatric Radiology
Publisher
Springer-Verlag
Publication Date
Apr 01, 2012
Volume
42
Issue
4
Pages
402–409
Identifiers
DOI: 10.1007/s00247-011-2298-6
PMID: 22120578
Source
Medline
License
Unknown

Abstract

Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.

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