Affordable Access

Publisher Website

Pearson syndrome in the neonatal period: two case reports and review of the literature.

Authors
Type
Published Article
Journal
Journal of Pediatric Hematology/Oncology
1077-4114
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
31
Issue
12
Pages
947–951
Identifiers
DOI: 10.1097/MPH.0b013e3181bbc4ef
PMID: 19881395
Source
Medline

Abstract

Pearson syndrome is a multiorgan mitochondrial cytopathy that results from defective oxidative phosphorylation owing to mitochondrial DNA deletions. Prognosis is severe and death occurs in infancy or early childhood. This article describes 2 cases with a severe neonatal onset of the disease. A review of the literature reveals the atypical presentation of the disease in the neonatal period, which is often overlooked and underdiagnosed.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments
F