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PCR and Restriction Endonuclease Assay for Detection of a Novel Mutation Associated with Sulfonamide Resistance in Neisseria meningitidis

Authors
  • Désirée E. Bennett
  • Mary T. Cafferkey
Publisher
American Society for Microbiology
Publication Date
Oct 01, 2003
Source
PMC
Keywords
License
Unknown

Abstract

We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.

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