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Patterns of variation in progestin in pregnant sheep.

Authors
  • Caton, D
  • Kalra, P S
Type
Published Article
Journal
The Journal of endocrinology
Publication Date
Jul 01, 1990
Volume
126
Issue
1
Pages
37–42
Identifiers
PMID: 2380654
Source
Medline
License
Unknown

Abstract

Patterns of variation in progestin concentrations were studied in pregnant sheep during the last half of gestation. In three sets of experiments, blood was drawn daily or every 4 h for 24 h or every 10 min for 8 h. Peripheral arterial concentration of progestin was examined for 'peaks' using the Pulsar program which identified peaks in daily samples and in samples collected every 10 min, though less often than in daily samples. Ovariectomy did not affect the frequency or character of the peaks. The data suggest that large variations in progestin concentrations occur during the last half of pregnancy. They are superimposed on a gradual increase in average concentration and last for 2 to 3 days.

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