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Patterns of Systemic Hypertension among Adults with Perinatally Acquired HIV.

Authors
  • Ryscavage, Patrick1
  • Macharia, Thomas1
  • Trinidad, Lino R1
  • Lovelace, Susan2
  • Tepper, Vicki2
  • Redfield, Robert1
  • 1 1 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • 2 2 Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
Type
Published Article
Journal
Journal of the International Association of Providers of AIDS Care (JIAPAC)
Publisher
SAGE Publications
Publication Date
Jan 01, 2017
Volume
16
Issue
1
Pages
3–7
Identifiers
DOI: 10.1177/2325957416668034
PMID: 27644759
Source
Medline
Keywords
License
Unknown

Abstract

Patients with perinatally acquired HIV may be at risk for the development of age-related non-AIDS diseases. The primary aim of this study was to describe patterns of systemic hypertension among a cohort of adults (≥18 years) with perinatally acquired HIV. A retrospective cohort study was conducted among adults (≥18 years) with perinatally acquired HIV infection. Primary outcomes included documentation of systemic hypertension as well as several additional non-AIDS-associated illnesses. Systemic hypertension incidence rates and rate ratios (RRs) were calculated among groups aged ≥18 and <18 years at the time of hypertension diagnosis. The overall prevalence of hypertension in the cohort (N = 109) was 26.6%, and the incidence rate of hypertension was significantly higher among those aged ≥18 years compared to those who are aged <18 years at the time of diagnosis (RR: 10.0, CI: 7.29-13.71). By multivariable analysis, only coexisting renal disease was associated with an increased risk of hypertension diagnosis.

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