Patterns of retention of particulate matter in lung tissues of patients with COPD: potential role in disease progression.
UBC James Hogg Research Centre, Heart and Lung Institute, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
UBC James Hogg Research Centre, Heart and Lung Institute, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: [email protected]
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We conclude that retained PM is widely distributed in lung tissues of subjects with COPD and that cigarette smoke exposure and airflow obstruction are associated with retention of PM in lung tissues. We attribute the downward trend in PM burden in severe COPD to either less deposition and retention or selective removal of PM containing tissues by emphysematous destruction.
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This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/21659433