These results corroborate the presence of genomic instability in SSc peripheral blood cells, as evaluated by increased DNA damage, and show that polymorphic sites of the XRCC1 and XRCC4 DNA repair genes may differentially influence DNA damage and the development of autoantibodies.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/24488411