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Patients With Short Bowel on Narcotics During 2 Randomized Trials Have Abdominal Complaints Independent of Teduglutide.

Authors
  • Fujioka, Ken1
  • Jeejeebhoy, Khursheed2
  • Pape, Ulrich-Frank3
  • Li, Benjamin4, 5
  • Youssef, Nader N6, 5
  • Schneider, Stéphane M7
  • 1 1 Department of Diabetes and Endocrinology, Scripps Clinic, San Diego, California, USA.
  • 2 2 Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada. , (Canada)
  • 3 3 Department of Hepatology & Gastroenterology, Charité University Medicine, Berlin, Germany. , (Germany)
  • 4 4 Department of Statistics, NPS Pharmaceuticals, Inc., Lexington, Massachusetts, USA.
  • 5 Amicus Therapeutics, Cranbury, New Jersey, USA, for BL and Digestive Healthcare Center, Hillsborough, New Jersey, USA, for NNY. , (Jersey)
  • 6 5 Clinical Research and Development, NPS Pharmaceuticals, Inc., Lexington, Massachusetts, USA.
  • 7 6 Gastroenterology and Clinical Nutrition, University of Nice-Sophia Antipolis, Nice, France. , (France)
Type
Published Article
Journal
JPEN. Journal of parenteral and enteral nutrition
Publication Date
Nov 01, 2017
Volume
41
Issue
8
Pages
1419–1422
Identifiers
DOI: 10.1177/0148607116663481
PMID: 27507402
Source
Medline
Keywords
License
Unknown

Abstract

These results suggest that patients with short bowel syndrome receiving narcotics have chronic GI complaints independent of teduglutide treatment. Data included in this analysis were derived from ClinicalTrials.gov NCT00081458 and NCT00798967 (EudraCT 2004-000438-35 and 2008-006193-15).

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