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Patient selection and outcomes using a low-dose intrathecal opioid trialing method for chronic nonmalignant pain.

Authors
Type
Published Article
Journal
Pain physician
Publication Date
Volume
14
Issue
4
Pages
343–351
Identifiers
PMID: 21785477
Source
Medline
License
Unknown

Abstract

Opioid taper and a 6 week opioid-free period may 1) improve long-term analgesia versus a combination of oral/ intrathecal drug delivery system therapy 2) it may be possible to maintain analgesia at microgram doses and 3) opioid tolerance may be reversible in 6 weeks. Further it appears that a dose response relationship for effective analgesia may be less than 400 μg of intrathecal morphine.

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