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Pathologic characteristics of human T-cell lymphotropic virus (HTLV)-related extranodal orofacial lymphomas.

Authors
  • Kurihara, K
  • Kohno, H
  • Miyamoto, N
  • Chikamori, Y
  • Kondo, T
Type
Published Article
Journal
Oral Surgery Oral Medicine Oral Pathology
Publisher
Elsevier
Publication Date
Aug 01, 1990
Volume
70
Issue
2
Pages
199–205
Identifiers
PMID: 2290649
Source
Medline
License
Unknown

Abstract

Eleven cases of extranodal orofacial lymphomas (EOFL), consisting of four HTLV-related and seven HTLV-unrelated EOFL, were investigated with respect to the immunohistochemical and clinical features. HTLV-related EOFL were of T-cell phenotype and were associated with a poorer prognosis than HTLV-unrelated EOFL, most of which were of B-cell origin. The appearance of giant cells with cerebriform nuclei was helpful in identifying HTLV-related EOFL. The relatively high incidence of T-cell type EOFL in our series was considered to be related to the high percentage of HTLV carriers in our district, an area endemic for adult T-cell leukemia-lymphoma.

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