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[Participation of innate immunity factors in pathogenesis of psoriatic lesions].

Authors
  • Katunina, O R
Type
Published Article
Journal
Arkhiv patologii
Publication Date
Jan 01, 2011
Volume
73
Issue
5
Pages
40–43
Identifiers
PMID: 22288172
Source
Medline
License
Unknown

Abstract

In the study concerning morphology and pathogenesis of psoriasis a number of Langerghans's cells (CD1a+) and an expression of toll-like receptors (TLR2, TLR4, TLR9) in psoriatic and normal skin has been estimated. A statistically significant increase of Langerghans's cells as well as the expression of TLR2 and TLR4 in psoriatic lesions has been founded out. The importance of observation in the pathogenesis of psoriasis has been discussed.

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