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Participation of granulocytes and humoral factors in resolution of platelet aggregates during endotoxemia.

Authors
  • Walker, R I
  • Fletcher, J R
  • Walden, D A
Type
Published Article
Journal
Experientia
Publication Date
Feb 15, 1980
Volume
36
Issue
2
Pages
255–256
Identifiers
PMID: 7371777
Source
Medline
License
Unknown

Abstract

Hydrogen peroxide generated by phagocytizing granulocytes can prevent platelet aggregation induced by ADP or collagen but not by endotoxin. Endotoxin tolerance enhances granulocyte mobilization in response to endotoxin and reduces aggregation induced by endotoxin but not ADP or collagen.

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