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Partial seizures associated with antiphospholipid antibodies in childhood.

Authors
  • Angelini, L
  • Granata, T
  • Zibordi, F
  • Binelli, S
  • Zorzi, G
  • Besana, C
Type
Published Article
Journal
Neuropediatrics
Publication Date
Oct 01, 1998
Volume
29
Issue
5
Pages
249–253
Identifiers
PMID: 9810560
Source
Medline
License
Unknown

Abstract

We report antiphospholipid antibody positivity in three of a consecutive series of 23 children presenting partial epileptic seizures. There was no clinical or serological evidence of systemic lupus erythematosus or other connective-tissue disease. Neither computed tomography nor magnetic resonance imaging revealed ischemic alteration. The presence of antiphospholipid antibodies in 3/23 children may indicate that immune-mediated neuronal damage could be a pathogenetic mechanism for partial epilepsy.

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