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[Parenthood diagnosis within a family. II. Determination of an optimal sequence of genetic markers (author's transl)].

Authors
Type
Published Article
Journal
Annales de génétique
Publication Date
Volume
24
Issue
1
Pages
21–24
Identifiers
PMID: 6971611
Source
Medline
License
Unknown

Abstract

The rapid discovery of new markers systems makes it impossible for financial reasons to study the polymorphism determination of all known genetic markers when dealing with parenthood problems. We propose to use the percentage of rejected subjects with respect to the (mother, children) set as a decision tool to define a sequence which provides the maximum information for the minimum cost. This decision rule is evaluated with a sample of 150 families whose polymorphism is determined on the same sequence of 20 genetic markers.

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