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Parasite antigenaemia and IgG4 antibodies to a filarial protease in an endemic human population in India.

Authors
  • Bal, M S
  • Beuria, M K
  • Mandal, N N
  • Das, M K
Type
Published Article
Journal
Journal of helminthology
Publication Date
Dec 01, 2003
Volume
77
Issue
4
Pages
287–290
Identifiers
PMID: 14627443
Source
Medline
License
Unknown

Abstract

Levels of circulating filarial antigen (Og4C3) and IgG4 antibodies to a filarial protease were determined in subjects of Wuchereria bancrofti exposed sera from Orissa, India. In addition to all individuals with antigenaemia (microfilaraemia), IgG4 antibodies were also detected in some individuals without antigenaemia. A 2-year longitudinal follow-up indicated that IgG4 seropositivity in asymptomatic amicrofilaraemics could be a risk factor for acquiring infection (antigenaemia).

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