Parasite antigenaemia and IgG4 antibodies to a filarial protease in an endemic human population in India.
- Authors
- Type
- Published Article
- Journal
- Journal of helminthology
- Publication Date
- Dec 01, 2003
- Volume
- 77
- Issue
- 4
- Pages
- 287–290
- Identifiers
- PMID: 14627443
- Source
- Medline
- License
- Unknown
Abstract
Levels of circulating filarial antigen (Og4C3) and IgG4 antibodies to a filarial protease were determined in subjects of Wuchereria bancrofti exposed sera from Orissa, India. In addition to all individuals with antigenaemia (microfilaraemia), IgG4 antibodies were also detected in some individuals without antigenaemia. A 2-year longitudinal follow-up indicated that IgG4 seropositivity in asymptomatic amicrofilaraemics could be a risk factor for acquiring infection (antigenaemia).