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Paraneoplastic sclerodermiform syndrome--case report.

Authors
  • Rovisco, João
  • Serra, Sara
  • Abreu, Pedro
  • Coutinho, Margarida
  • Santiago, Tânia
  • Inês, Luís
  • da Silva, José António Pereira
Type
Published Article
Journal
Acta reumatológica portuguesa
Publication Date
Jan 01, 2014
Volume
39
Issue
1
Pages
87–90
Identifiers
PMID: 24811467
Source
Medline
License
Unknown

Abstract

Occasionally, auto-immune diseases may emerge as paraneoplastic syndromes. This is especially recognized in the case of polymyositis/dermatomyostis, but it is an extremely rare event in systemic sclerosis (SSc). The authors report the case of a sixty-year-old woman who presented with Raynaud's phenomenon and rapidly progressing skin thickness of the forearms, hands and lower limbs. Patient evaluation revealed a colorectal carcinoma. The patient was referred to the oncology department. This concomitance of cancer and SSc with rapid progression of the latter, suggests that the scleroderma might have a paraneoplastic origin. Such an hypothesis deserves consideration in every case as early diagnosis may be decisive to control the progression of either disease.

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