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Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells

Authors
  • Tang, Qingyuan
  • Schweitzer, Jeffrey S.
  • Song, Bin
Type
Published Article
Journal
Stem Cell Reports
Publisher
Elsevier
Publication Date
Sep 29, 2022
Volume
17
Issue
10
Pages
2167–2171
Identifiers
DOI: 10.1016/j.stemcr.2022.09.002
PMID: 36179693
PMCID: PMC9561634
Source
PubMed Central
Disciplines
  • Commentary
License
Unknown

Abstract

In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO , to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022).

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