Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1.
- Published Article
- Publication Date
Aug 01, 2005
GLP-1 and pdx-1 work together to induce insulin-producing cells from IMPE cells, which bear unique characteristics of pancreatic ductal cells. The results suggest that GLP-1 may be another important determiner of pancreatic endocrine differentiation as is pdx-1.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/16153418