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Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium

Authors
  • Punia, Lavisha
  • Ramesh, Karu
  • G, Satyanarayana
Publication Date
Jan 01, 2020
Source
RAIITH
Keywords
License
Unknown

Abstract

Isochromenes have been synthesized using palladium-catalyzed C–C and C–O bond forming reactions starting from ortho-bromo tertiary benzylic alcohols and internal acetylenes. Notably, this domino process is feasible by using the green solvent, water. The protocol exhibited a broad substrate scope and afforded various isochromenes.

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