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Palladium-catalyzed synthesis of N-tert-prenylindoles.

Authors
  • Johnson, Kirsten F
  • Van Zeeland, Ryan
  • Stanley, Levi M
Type
Published Article
Journal
Organic Letters
Publisher
American Chemical Society
Publication Date
Jun 07, 2013
Volume
15
Issue
11
Pages
2798–2801
Identifiers
DOI: 10.1021/ol4011344
PMID: 23714013
Source
Medline
License
Unknown

Abstract

Palladium-catalyzed N-tert-prenylations of indoles, tricarbonylchromium-activated indoles, and indolines that occur in high yields (up to 94%) with high tert-prenyl-to-n-prenyl selectivity (up to 12:1) are reported.

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