Oxygen sensing: Protein degradation meets retrograde signaling.
- Authors
- Type
- Published Article
- Journal
- Current biology : CB
- Publication Date
- Mar 28, 2022
- Volume
- 32
- Issue
- 6
- Identifiers
- DOI: 10.1016/j.cub.2022.02.047
- PMID: 35349816
- Source
- Medline
- Language
- English
- License
- Unknown
Abstract
A new study shows that mitochondrial retrograde signaling relies on strongly compartmentalized individual pathways previously not taken into account. This involves a link between mitochondrial oxygen consumption and cytosolic oxygen sensing via the N-degron pathway. Copyright © 2022 Elsevier Inc. All rights reserved.