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Outlooks on Three-Dimensional Printing for Ocular Biomaterials Research.

Authors
  • Fenton, Owen S1
  • Paolini, Marion1
  • Andresen, Jason L1, 2
  • Müller, Florence J1
  • Langer, Robert1, 3, 4, 5
  • 1 Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • 2 Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • 3 Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • 4 Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • 5 Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Jan 01, 2020
Volume
36
Issue
1
Pages
7–17
Identifiers
DOI: 10.1089/jop.2018.0142
PMID: 31211652
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Given its potential for high-resolution, customizable, and waste-free fabrication of medical devices and in vitro biological models, 3-dimensional (3D) bioprinting has broad utility within the biomaterials field. Indeed, 3D bioprinting has to date been successfully used for the development of drug delivery systems, the recapitulation of hard biological tissues, and the fabrication of cellularized organ and tissue-mimics, among other applications. In this study, we highlight convergent efforts within engineering, cell biology, soft matter, and chemistry in an overview of the 3D bioprinting field, and we then conclude our work with outlooks toward the application of 3D bioprinting for ocular research in vitro and in vivo.

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