Affordable Access

deepdyve-link
Publisher Website

Outcomes of staged hepatectomies for liver malignancy.

Authors
  • Albati, Naif A1
  • Korairi, Ali A2
  • Hasan, Ibrahim Al2
  • Almodhaiberi, Helayel K2
  • Algarni, Abdullah A
  • 1 Abdullah A Algarni, Hepatobiliary and Liver Transplant Unit, Department of General Surgery, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia. [email protected] , (Saudi Arabia)
  • 2 Abdullah A Algarni, Hepatobiliary and Liver Transplant Unit, Department of General Surgery, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia. , (Saudi Arabia)
Type
Published Article
Journal
World Journal of Hepatology
Publisher
Baishideng Publishing Group Co (World Journal of Hepatology)
Publication Date
Jun 27, 2019
Volume
11
Issue
6
Pages
513–521
Identifiers
DOI: 10.4254/wjh.v11.i6.513
PMID: 31293719
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Liver malignancies are the fifth most common cause of death worldwide. Surgical intervention with curative intent is the treatment of choice for liver tumors as it provides long-term survival. However, only 20% of patients with metastatic liver lesions can be managed by curative liver resection. In most of the cases, hepatectomy is not feasible because of insufficient future liver remnant (FLR). Two-stage hepatectomy is advocated to achieve liver resection in a patient who is considered to not be a candidate for resection. Procedures of staged hepatectomy include conventional two-stage hepatectomy, portal vein embolization, and associating liver partition and portal vein ligation for a staged hepatectomy. Technical success is high for each of these procedures but variable between them. All the procedures have been reported as being effective in achieving a satisfactory FLR and completing the second-stage resection. Moreover, the overall survival and disease-free survival rates have improved significantly for patients who were otherwise considered nonresectable; yet, an increase in the morbidity and mortality rates has been observed. We suggest that this type of procedure should be carried out in high-flow centers and through a multidisciplinary approach. An experienced surgeon is key to the success of those interventions.

Report this publication

Statistics

Seen <100 times