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Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma

Authors
  • Loayza-Gamboa, Waldo1, 2
  • Martel-Ramirez, Vladimir1, 3
  • Inga-Condezo, Vanessa1, 3
  • Valderrama-Albino, Vanessa2, 3
  • Alvarado-Villacorta, Rosa2, 3
  • Valera-Cornejo, Diego2, 3
  • 1 Instituto Nacional de Oftalmología “Francisco Contreras Campos”, Lima
  • 2 Clínica Vista, Lima
  • 3 Faculty of medicine, Universidad Peruana Cayetano Heredia, Lima , (Peru)
Type
Published Article
Journal
Clinical Ophthalmology (Auckland, N.Z.)
Publisher
Dove
Publication Date
Oct 02, 2020
Volume
14
Pages
3009–3016
Identifiers
DOI: 10.2147/OPTH.S272298
PMID: 33061287
PMCID: PMC7537843
Source
PubMed Central
Keywords
License
Green

Abstract

Purpose To describe the clinical outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy (GATT) with phacoemulsification in patients with open-angle glaucoma. Methods Retrospective study of patients with cataract and open-angle glaucoma treated with GATT and phacoemulsification with intraocular lens (IOL) implantation. Patients with neovascular glaucoma, corneal decompensation, unstable IOL, and with bleeding disorders were excluded. The cumulative probability of failure was the primary outcome. Secondary outcomes were the complete success rate, the mean change on intraocular pressure (IOP), best-corrected visual acuity (BCVA) and number of glaucoma medications at the last follow-up. The frequency of complications was also recorded. Results Thirty two eyes (25 patients) were included. Nineteen (59.3%) were females, with a mean age of 73.4±12.4 (23–87 years) and a mean baseline BCVA of 1.1±0.75 (0.3–3) LogMAR units. The cumulative probability of failure was 3.2% at 1 month and 6.3% at 6 and 12 months. Sixty-eight and 65.5% of eyes achieved complete success at 3 and 6 months, respectively. The reduction of IOP and number of glaucoma medications at 6 months were statistically significant (p<0.0001 and p=0.0002, respectively). There was a statistically significant improvement of BCVA (from 1.1±0.7 to 0.4±0.7) at 6 months (p<0.0001). IOP spikes (18.7%) and transient hyphema (9.3%) were the most common complications. Conclusion Combined GATT with cataract surgery reduced the IOP and was associated with low failure rates and few ocular complications. This procedure offers the advantage to avoid the need for a bleb, scleral, or conjunctival incision, allowing the possibility for future glaucoma procedures.

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