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Osteoblasts mineralization and collagen matrix are conserved upon specific Col1a2 silencing

Authors
  • Maruelli, Silvia
  • Besio, Roberta
  • Rousseau, Julie
  • Garibaldi, Nadia
  • Amiaud, Jérôme
  • Brulin, Bénédicte
  • Layrolle, Pierre
  • Escriou, Virginie
  • Rossi, Antonio
  • Trichet, Valerie
  • Forlino, Antonella
Type
Published Article
Journal
Matrix Biology Plus
Publisher
Elsevier
Publication Date
Jan 31, 2020
Volume
6-7
Identifiers
DOI: 10.1016/j.mbplus.2020.100028
PMID: 33543025
PMCID: PMC7852305
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown

Abstract

• Identification of a specific and efficient Col1a2 siRNA • Silencing of Col1a2 allows osteoblasts mineralization. • Col1a2 silencing is not impairing matrix deposition in vivo .

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