Affordable Access

Access to the full text

Osteitis: a retrospective feasibility study comparing single-source dual-energy CT to MRI in selected patients with suspected acute gout

Authors
  • Diekhoff, Torsten1, 2
  • Scheel, Michael1
  • Hermann, Sandra3
  • Mews, Jürgen4
  • Hamm, Bernd1
  • Hermann, Kay-Geert A.1
  • 1 Humboldt-Universität zu Berlin, Freie Universität Berlin, Department of Radiology, Charité - Universitätsmedizin Berlin Campus Mitte, Berlin, Germany , Berlin (Germany)
  • 2 Charité - Universitätsmedizin Berlin, Department of Radiology (CCM), Charitéplatz 1, Berlin, 10117, Germany , Berlin (Germany)
  • 3 Charité – Universitätsmedizin Berlin Campus Mitte, Department of Rheumatology and Clinical Immunology, Berlin, Germany , Berlin (Germany)
  • 4 Toshiba Medical Systems Europe, BV, Zilverstraat 1, 2701RP, Zoetermeer, Netherlands , Zoetermeer (Netherlands)
Type
Published Article
Journal
Skeletal Radiology
Publisher
Springer-Verlag
Publication Date
Nov 21, 2016
Volume
46
Issue
2
Pages
185–190
Identifiers
DOI: 10.1007/s00256-016-2533-1
Source
Springer Nature
Keywords
License
Green

Abstract

ObjectiveDual-energy computed tomography detects tophi in patients with chronic gout. However, other information that can be obtained from the same scan is not the focus of the current research, e.g., the detection of bone marrow edema (BME) using virtual bone marrow imaging (VBMI). The aim of this study was to evaluate if BME in patients with acute arthritis can be detected with VBMI using magnetic resonance imaging (MRI) as the standard of reference.Materials and methodsThis retrospective study included 11 patients who underwent both MRI and dual-energy computed tomography (mean interval of 40 days). BME in MRI (standard of reference) and VBMI was judged independently by two different blinded readers. φ-correlation coefficient and Cohen’s κ were performed for statistical analysis. Approval was waived by the IRB.ResultsTwo patients with a final diagnosis of RA and one with septic arthritis showed osteitis on MRI and VBMI. However, in each case, there were individual bones identified with osteitis on MRI but not VBMI. Three additional patients with the final diagnosis of RA were identified correctly as negative for BME. There was a good correlation between both modalities (φ = 0.8; κ = 0.8). Inter-rater reliability was excellent for both modalities (κ = 0.9).ConclusionsWe have shown that detecting osteitis using VBMI is feasible in patients with inflammatory arthritis. Further studies are needed on larger, more-targeted populations to better define the indications, accuracy, and added value of this technique.

Report this publication

Statistics

Seen <100 times