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Origin of mouse melanomas.

Authors
  • Larue, Lionel
Type
Published Article
Journal
Journal of Investigative Dermatology
Publisher
Elsevier
Publication Date
Sep 01, 2012
Volume
132
Issue
9
Pages
2135–2136
Identifiers
DOI: 10.1038/jid.2012.221
PMID: 22895447
Source
Medline
License
Unknown

Abstract

In humans, melanomas are found mostly in the epidermis, whereas mouse melanomas are found in the dermis. It is, however, possible to force mouse melanomas to develop more efficiently in the epidermis. The histological location of a melanoma when discovered, whether in the epidermis or dermis, does not necessarily reflect the location of the original cell.

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