Multiple Input Multiple Output (MIMO) systems have recently emerged as a key technology in wireless communication systems for increasing both data rates and system performance. There are many schemes that can be applied to MIMO systems such as space time block codes, space time trellis codes, and the Vertical Bell Labs Space-Time Architecture (V-BLAST). This paper proposes a novel signal detector scheme called MIMO detectors to enhance the performance in MIMO channels. We study the general MIMO system, the general V-BLAST architecture with Maximum Likelihood (ML), Zero- Forcing (ZF), Minimum Mean- Square Error (MMSE), and Ordered Successive Interference Cancellation (SIC) detectors and simulate this structure in Rayleigh fading channel. Also compares the performances of MIMO system with different modulation techniques in Fading and AWGN channels. Base on frame error rates and bit error rates, we compare the performance and the computational complexity of these schemes with other existence model.Simulations shown that V-BLAST implements a detection technique, i.e. SIC receiver, based on ZF or MMSE combined with symbol cancellation and optimal ordering to improve the performance with lower complexity, although ML receiver appears to have the best SER performance-BLAST achieves symbol error rates close to the ML scheme while retaining the lowcomplexity nature of the V-BLAST.