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Optical coherence tomography angiography in uveitis

Authors
  • Tranos, Paris1
  • Karasavvidou, Evdoxia-Maria1, 2
  • Gkorou, Olga1
  • Pavesio, Carlos3
  • 1 Ophthalmica Clinic, Vas.Olgas 196 and Ploutonos, Thessaloniki, 546 55, Greece , Thessaloniki (Greece)
  • 2 Hippokrateio General Hospital of Thessaloniki, 49 Konstantinoupoleos Street, Thessaloniki, 546 42, Greece , Thessaloniki (Greece)
  • 3 Moorfields Eye Hospital, 162 City Rd, London, EC1V 2PD, UK , London (United Kingdom)
Type
Published Article
Journal
Journal of Ophthalmic Inflammation and Infection
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Dec 23, 2019
Volume
9
Issue
1
Identifiers
DOI: 10.1186/s12348-019-0190-y
Source
Springer Nature
Keywords
License
Green

Abstract

Before the introduction of optical coherence tomography angiography (OCTA) in the early 2000s, dye-based angiography was considered the “gold standard” for the diagnosis and monitoring of ocular inflammation. OCTA is a novel technique, which demonstrates capillary networks based on the amount of light returned from moving blood cells, providing further information on pathophysiological changes in uveitis. The aim of this review is to describe the basic principles of OCTA and its application to ocular inflammatory disorders. It particularly emphasizes on its contribution not only in the diagnosis and management of the disease but also in the identification of possible complications, comparing it with fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Although the advent of OCTA has remarkably enhanced the assessment of uveitic entities, we highlight the need for further investigation in order to better understand its application to these conditions.

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