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Opening New Scenarios for Human MAO Inhibitors.

Authors
  • De Monte, Celeste
  • D Ascenzio, Melissa
  • Guglielmi, Paolo
  • Mancini, Veronica
  • Carradori, Simone1
  • 1 Department of Pharmacy, "G. D'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy. [email protected] , (Italy)
Type
Published Article
Journal
Central nervous system agents in medicinal chemistry
Publication Date
Jan 01, 2016
Volume
16
Issue
2
Pages
98–104
Identifiers
PMID: 26320583
Source
Medline
Language
English
License
Unknown

Abstract

Despite the considerable interest in the search of new and potent human MAO inhibitors, an increasing number of research works deal with new therapeutic and analytical approaches regarding these molecules. Our interest was focused on the detailed analysis of (i) new pharmacological options for selective hMAO inhibitors; (ii) innovative analytical procedures to discover/screen hMAO inhibitors, and (iii) the recent possibility of using labeled hMAO inhibitors to unravel neurodegenerative diseases and drug distribution. All these three aspects could open new scenarios stimulating the interest of researchers in this field.

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