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[Onset of a fulminant malignant hyperthermia crisis. Case report of a 74-year-old patient with previously subclinical central core disease].

Authors
  • Wejbora, M
  • Bornemann-Cimenti, H
  • Lessel, D
  • Mandl, C
  • Voit-Augustin, H
  • Schwarz, G
Type
Published Article
Journal
Der Anaesthesist
Publisher
Springer-Verlag
Publication Date
Jan 01, 2013
Volume
62
Issue
1
Pages
34–38
Identifiers
DOI: 10.1007/s00101-012-2107-0
PMID: 23247425
Source
Medline
License
Unknown

Abstract

Malignant hyperthermia (MH) is a latent, autosomal dominant inherited syndrome of skeletal musculature which results in excessive hypermetabolism induced by halogenated anesthetic agents and depolarizing muscle relaxants and is caused by an uncontrolled intramuscular calcium release. This case report focuses on the description of symptoms of a fulminant MH crisis. A possible link between central core disease (CCD) and the clinical severity of MH crisis is postulated in this paper.

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