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One-step production of darunavir solid dispersion nanoparticles coated with enteric polymers using electrospraying.

Authors
  • Nguyen, Duong Nhat1
  • Palangetic, Ljiljana2
  • Clasen, Christian2
  • Van den Mooter, Guy1
  • 1 Department of Pharmaceutical and Pharmacological Sciences, Drug Delivery and Disposition, KU Leuven - University of Leuven, Leuven, Belgium.
  • 2 Department of Chemical Engineering, KU Leuven - University of Leuven, Leuven, Belgium.
Type
Published Article
Journal
The Journal of pharmacy and pharmacology
Publication Date
May 2016
Volume
68
Issue
5
Pages
625–633
Identifiers
DOI: 10.1111/jphp.12459
PMID: 26272245
Source
Medline
Keywords
License
Unknown

Abstract

This study showed the potential of coaxial electrospraying for encapsulating solid dispersions within core-shell structured nanoparticles.

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