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Once daily dose gentamicin in neonates - is our dosing correct?

Authors
  • Serane, Tiroumourougane V
  • Zengeya, Stanley
  • Penford, Gemma
  • Cooke, Jane
  • Khanna, Gitika
  • McGregor-Colman, Elle
Type
Published Article
Journal
Acta Paediatrica
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jul 01, 2009
Volume
98
Issue
7
Pages
1100–1105
Identifiers
DOI: 10.1111/j.1651-2227.2009.01297.x
PMID: 19397541
Source
Medline
License
Unknown

Abstract

A dose of 4 mg/kg/day produces serum gentamicin levels outside the therapeutic range in two-fifths of neonates between 32 and 36 +/- 6 weeks. A single dose of 4 mg/kg/day of gentamicin is appropriate for term babies and probably excessive for 32-36 weeks' neonates.

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