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Ocular Drug Distribution and Safety of a Noninvasive Ocular Drug Delivery System of Dexamethasone Sodium Phosphate in Rabbit.

Authors
  • Papangkorn, Kongnara1
  • Higuchi, John W1
  • Brar, Balbir1
  • Higuchi, William I1
  • 1 Aciont, Inc. , Salt Lake City, Utah.
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Feb 12, 2018
Identifiers
DOI: 10.1089/jop.2017.0093
PMID: 29432054
Source
Medline
Keywords
License
Unknown

Abstract

DSP can be administered safely and effectively into the rabbit eye with the Visulex system. Treatment duration and DSP concentration are important factors in achieving therapeutic levels. Repeat applications of DSP-Visulex are safe and well tolerated for weekly administrations over 4-12 weeks. DSP-Visulex has clinical potential for the noninvasive treatment of ocular diseases.

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