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OCT angiography for the diagnosis and management of choroidal neovascularization secondary to choroideremia.

Authors
  • Ranjan, Ratnesh1
  • Verghese, Shishir1
  • Salian, Romit1
  • Manayath, George J1
  • Saravanan, Veerappan R1
  • Narendran, Venkatapathy1
  • 1 Department of Retina and Vitreous Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India. , (India)
Type
Published Article
Journal
American journal of ophthalmology case reports
Publication Date
Jun 01, 2021
Volume
22
Pages
101042–101042
Identifiers
DOI: 10.1016/j.ajoc.2021.101042
PMID: 33681533
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To describe the multimodal imaging findings and treatment outcomes in choroidal neovascularization secondary to Choroideremia. A 13-year-old male presented with reduced visual acuity in the left eye. He gave a history of nyctalopia. His best-corrected visual acuity (BCVA) was 20/20 in the right eye and 20/40 in the left eye. Based on multimodal imaging, the diagnosis of choroideremia in both eyes with a subfoveal choroidal neovascularization in the left eye was made. He underwent five intravitreal anti-vascular endothelial growth factor (VEGF) injections of Ranibizumab over a period of 3 years, with the final injection given due to recurrence of neovascularization. Post-treatment, his BCVA improved to 20/20 in the left eye with regression of the neovascular network. This case highlights the role of OCTA in diagnosis of choroidal neovascularization in choroideremia as well as its successful management with anti-VEGF injections with long term follow up. © 2021 The Authors.

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