Affordable Access

deepdyve-link
Publisher Website

Occupational radiation exposure and thyroid cancer incidence in a cohort of U.S. radiologic technologists, 1983-2013.

Authors
  • Kitahara, Cari M1
  • Preston, Dale L2
  • Neta, Gila3
  • Little, Mark P1
  • Doody, Michele M1
  • Simon, Steven L1
  • Sigurdson, Alice J1
  • Alexander, Bruce H4
  • Linet, Martha S1
  • 1 Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • 2 Hirosoft International, Eureka, CA.
  • 3 Division of Cancer Control and Population Sciences, Implementation Science, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • 4 Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN.
Type
Published Article
Journal
International Journal of Cancer
Publisher
Wiley (John Wiley & Sons)
Publication Date
Nov 01, 2018
Volume
143
Issue
9
Pages
2145–2149
Identifiers
DOI: 10.1002/ijc.31270
PMID: 29355960
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Although childhood exposure to ionizing radiation is a well-established risk factor for thyroid cancer, the risk associated with adulthood exposure remains unclear. We prospectively examined the association between cumulative, low-to-moderate dose occupational radiation exposure to the thyroid and thyroid cancer incidence in the U.S. Radiologic Technologists cohort. The study included 89,897 members who completed at least two of four mailed questionnaires and were cancer-free at the time of the first questionnaire. Cumulative occupational thyroid radiation dose (mean = 57 mGy, range = 0-1,600 mGy) was estimated based on self-reported work histories, historical data and, during the years 1960-1997, 783,000 individual film badge measurements. During follow-up, we identified 476 thyroid cancer cases. We used Poisson regression to estimate excess relative risk of thyroid cancer per 100 milliGray (ERR/100 mGy) absorbed dose to the thyroid gland. After adjusting for attained age, sex, birth year, body mass index and pack-years smoked, we found no association between thyroid dose and thyroid cancer risk (ERR/100 mGy = -0.05, 95% CI <-0.10, 0.34). In this large cohort study of radiologic technologists, protracted, low-to-moderate dose ionizing radiation exposure to the thyroid gland in adulthood was not associated with an increased risk of thyroid cancer. © 2018 UICC.

Report this publication

Statistics

Seen <100 times