Introduction: Eclampsia affects 5 to 10% of all pregnancies and contributes to 10 to 15% of maternal deaths worldwide. Estimated case fatality rate due to eclampsia is 14 times higher in developing countries compared to developed countries. Eclampsia is a potentially fatal disorder of pregnant women that has been prevalent since the time of Hippocrates; it remains an important cause of maternal mortality throughout the world, accounting for about 50,000 deaths worldwide. This study was aimed to assess the level of nurse’s knowledge regarding management of eclampsia. Materials and Methods: A descriptive cross-sectional study was carried out from September 2016 to January 2017. A total of 105 nurses were selected purposively during the period of this study, the data was collected using self-administered semi-structured questionnaire and it was analysed using SPSS version 20.0. Results: In this study the mean of the respondents was 31.6 years. Slightly above half (51.4%) of the respondents were unmarried and the rest of them were married. Majority of the participants (52.5%) had B.Sc. nursing; however 70.5% of the respondents knew about the current management of Eclampsia. Conclusion: The findings of this study revealed that the majority of the nurses that participated in this study had somehow enough level of knowledge about the management of eclampsia.