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Nucleosome positioning: resources and tools online

Authors
  • Teif, Vladimir B.
Type
Preprint
Publication Date
Sep 08, 2015
Submission Date
Aug 27, 2015
Identifiers
arXiv ID: 1508.06916
Source
arXiv
License
Yellow
External links

Abstract

Nucleosome positioning is an important process required for proper genome packing and its accessibility to execute the genetic program in a cell-specific, timely manner. In the recent years hundreds of papers have been devoted to the bioinformatics, physics and biology of nucleosome positioning. The purpose of this review is to cover a practical aspect of this field, namely to provide a guide to the multitude of nucleosome positioning resources available online. These include almost 300 experimental datasets of genome-wide nucleosome occupancy profiles determined in different cell types and more than 40 computational tools for the analysis of experimental nucleosome positioning data and prediction of intrinsic nucleosome formation probabilities from the DNA sequence. A manually curated, up to date list of these resources will be maintained at http://generegulation.info.

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