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Nucleoporin Condensates Drive Nuclear Pore Complex Assembly in Oocytes

Authors
  • Mobbs, George W.
  • Hoelz, André
Publication Date
Apr 01, 2020
Source
Caltech Authors
License
Unknown

Abstract

Oocytes stockpile nuclear pore complexes (NPCs) in cytoplasmic membrane sheets called annulate lamellae (AL) in preparation for rapid cell cycles during embryogenesis. Recently, Hampoelz et al. reported that AL–NPC assembly depends on the coordinated formation, transport, and interaction of biomolecular condensates containing distinct sets of nucleoporins.

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