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Nuclear localization of cancer stem cell marker CD133 in triple-negative breast cancer: a case report.

Authors
  • Cantile, Monica
  • Collina, Francesca
  • D'Aiuto, Massimiliano
  • Rinaldo, Massimo
  • Pirozzi, Giuseppe
  • Borsellino, Carmela
  • Franco, Renato
  • Botti, Gerardo
  • Di Bonito, Maurizio
Type
Published Article
Journal
Tumori Journal
Publisher
SAGE Publications
Publication Date
Jan 01, 2013
Volume
99
Issue
5
Identifiers
DOI: 10.1700/1377.15325
PMID: 24362879
Source
Medline
License
Unknown

Abstract

Nuclear localization of CD133 may be an indicator of poor prognosis in TN breast cancer, as it is known that surface molecules, when moving into the nucleus, can act as transcriptional regulators by interfering with molecular pathways directly connected to the proliferation and differentiation of tumor cells.

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