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NRP1 cripples immunological memory

Authors
  • Acharya, Nandini1
  • Anderson, Ana C.1
  • 1 Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA , Boston (United States)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Jul 28, 2020
Volume
21
Issue
9
Pages
972–973
Identifiers
DOI: 10.1038/s41590-020-0759-5
Source
Springer Nature
License
Yellow

Abstract

Durable responses to immunotherapy require the development of robust CD8+ T cell memory. A new study indicates that NRP1 differs from other checkpoint receptors as it functions as a checkpoint for the generation of memory.

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