Novel HLA-DRB1 alleles revealed by sequencing based typing, DRB1*04053 and DRB1*1143.
- Published Article
- Publication Date
Apr 01, 2002
We report the discovery of two HLA-DRB1 alleles by sequencing based typing (SBT). DRB1*04053 differs from previously reported DRB1 alleles by a single synonymous nucleotide substitution, resulting in a unique polymorphism at codon 93. DRB1*1143 differs from previously identified DRB1 alleles by a single non-synonymous nucleotide substitution, resulting in a polymorphism observed in other DRB1 and DRB3 alleles1.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/12135441