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Novel endoscopic imaging techniques toward in vivo observation of living cancer cells in the gastrointestinal tract.

Authors
  • Inoue, Haruhiro
  • Kudo, Shin-ei
  • Shiokawa, Akira
Type
Published Article
Journal
Clinical Gastroenterology and Hepatology
Publisher
Elsevier
Publication Date
Jul 01, 2005
Volume
3
Issue
7 Suppl 1
Identifiers
PMID: 16013000
Source
Medline
License
Unknown

Abstract

It is now possible to perform microscopic imaging of living cells from both normal mucosa and malignant tissue in the gastrointestinal tract. Endocytoscopy is a catheter-type contact endoscope that has more than 1000-fold magnifying power and can pass through the working channel of the straight-view endoscope. In esophageal cells, the nucleus, cell body, and even the nucleolus were clearly distinguished with high-resolution images comparable with those of conventional cytology. This novel technology has the potential to provide histologic diagnoses during endoscopic examinations, similar to those obtained currently by conventional histology techniques.

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